Review: Breaking From Bisphosphonates
نویسندگان
چکیده
منابع مشابه
Treatment of bisphosphonates - associated osteonecrosis Mini - review
This mini-review will focus on the management of a patient with bisphosphonate-associated osteonecrosis (BON). In order to review the subject the authors report a case of a patient with prostate cancer and metastatic bone disease who was treated with zoledronic acid. Prior to cancer the patient was treated with risedronate for osteopenia but had discontinued this treatment when cancer was diagn...
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BACKGROUND Osteoporosis and cardiovascular disease are interconnected entities with pathophysiological similarities. Bisphosphonates are therapeutic options available for resorptive bone diseases; however, experimental evidence has demonstrated a role for bisphosphonates in the inhibition of atherogenesis. METHODS A systematic review of the vascular effects of bisphosphonates on atheroscleros...
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The discovery and development of the bisphosphonates (BPs) as a major class of drugs for the treatment of bone diseases has been a fascinating journey that is still not over. In clinical medicine, several BPs are established as the treatments of choice for various diseases of excessive bone resorption, including Paget's disease of bone, myeloma and bone metastases, and osteoporosis. Bisphosphon...
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Bisphosphonates (BPs) are synthetic analogues of naturally occurring pyrophosphate compounds. They are used in clinical practice to inhibit bone resorption in bone metastases, osteoporosis, and Paget's disease. BPs induce apoptosis because they can be metabolically incorporated into nonhydrolyzable analogues of adenosine triphosphate. In addition, the nitrogen-containing BPs (N-BPs), second-gen...
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We present a class of four-dimensional models, with a non-supersymmetric spectrum, in which the radiative corrections to the Higgs mass are not sensitive, at least at one-loop, to the UV completion of the theory. At one loop, Yukawa interactions of the top quark contribute to a finite and negative Higgs squared mass which triggers the electroweak symmetry breaking, as in softly broken supersymm...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatology
سال: 2017
ISSN: 2326-5191
DOI: 10.1002/art.39967